Which statement about methadone is correct?

The assertion that all of the statements regarding methadone are correct is validated based on the historical context and chemical classification of the drug.

Methadone was indeed synthesized during World War II as part of a response to the morphine shortage that arose due to the war's impact on supply chains. This development aimed to create an effective analgesic that could mitigate the challenges faced in pain management during that time.

Furthermore, methadone was introduced to the United States in 1947, marking the beginning of its use in clinical settings, including pain management and later its role in opioid addiction treatment.

In terms of chemistry, methadone belongs to a class of synthetic opioids and is structurally similar to morphine, although it has different pharmacological properties and a longer duration of action.

Hence, stating that all the mentioned facts are true accurately encapsulates the multifaceted history and classification of methadone, making this option the most comprehensive and correct choice.